Tag
Supplement safety
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High-dose vitamin D did not slow advanced bowel cancer
A 455-patient phase 3 trial run through the US National Clinical Trials Network added high-dose vitamin D3 to standard chemotherapy for metastatic colorectal cancer. It did not delay progression.
Aug 6, 2026
Vitamin D: uses, evidence, dosing and safety
Vitamin D is the most-studied supplement there is, and the pattern across thirteen uses is almost always the same: correcting a deficiency helps, and adding more on top of enough does not.
Aug 6, 2026
Coenzyme Q10: uses, evidence, dosing and safety
CoQ10 has decent evidence for the serious condition almost nobody buys it for, and it fails at the one thing almost everybody buys it for. Statin muscle pain is the claim that does not hold up.
Aug 5, 2026
NAC: uses, evidence, dosing and safety
NAC is a hospital antidote sold as a supplement, and the two are not the same claim. It saves lives in paracetamol overdose. For almost everything it is marketed for, the evidence is thin or uncertain.
Aug 5, 2026